Differences

This shows you the differences between two versions of the page.

Link to this comparison view

Both sides previous revision Previous revision
Next revision
Previous revision
Next revision Both sides next revision
publication:juan [2019/05/29 19:30]
游文萱
publication:juan [2020/03/26 04:34]
游文萱
Line 2: Line 2:
  
 ===== Journal Papers / 期刊論文 ===== ===== Journal Papers / 期刊論文 =====
-  - Huang, C.-T., Hsieh, C.-H., ​Chung, Y.-H., ​OyangY.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) "Perturbational gene-expression signatures for combinatorial drug discovery" //iScience// (**Cell Press**, doi: 10.1016/j.isci.2019.04.039). +  - Yin, C.-F., Kao, S.-C., Hsu, C.-L., Cheung, C. H.Y., Chang, Y.-W., Huang, ​H.-C.*__**JuanH.-F.**__* (2020) "​Phosphoproteome analysis reveals dynamic heat shock protein 27 phosphorylation in tanshinone IIA-induced cell death" //Journal of Proteome Research// (in press) 
-  - Huang, C.-T., Hsieh, C.-H., Lee, W.-C., Liu, Y.-L., Yang, T.-S., Hsu, W.-M., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* "​Therapeutic targeting of non-oncogene dependencies in high-risk neuroblastoma"​ //Clinical Cancer Research// (Accepted).+  - Lee, P.-C. Chen, S.-T., Kuo, T.-C., Lin, T.-C., Lin, M.-C., Huang, ​J., Hung, J.-S., Hsu, C.-L., __**Juan, H.-F.**__, Lee, P.-H., and Huang, M.-C. (2020) "​C1GALT1 is associated with poor survival and promotes soluble Ephrin A1-mediated cell migration through activation of EPHA2 in gastric cancer"​ //​Oncogene//​ (in press).  
 +  - Lee, W.-H., Chen, K.-P., Wang, K., Huang, H.-C.*, __**Juan, H.-F.**__* (2020) "​Characterizing the cancer-associated microbiome with small RNA sequencing data" //​Biochemical and Biophysical Research Communications//​ 522:​776-782. 
 +  - Chang, H.-C., Huang, H.-C., __**Juan, H.-F.**__*, Hsu, C.-L* (2019) "Investigating the role of super-enhancer RNAs underlying embryonic stem cell differentiation" //BMC Genomics// 20(Suppl 10):896. 
 +  - Hsieh, C.-H., Cheung, C. H. Y., Liu, Y.-L., Hou, C.-L., Hsu, C.-L., Huang, C.-T., Yang, T.-S., Chen, S.-F., Chen, C.-N., Hsu, W.-M.*, Huang, H.-C.*, __**JuanH.-F.**__* (2019) "​Quantitative proteomics of Th-MYCN transgenic mice reveals aurora kinase inhibitor altered metabolic pathways and enhanced ACADM to suppress neuroblastoma progression" ​//Journal of Proteome Research// 18(11):​3850-3866. 
 +  - Cheung, HY. C., Hsu, C.-L., Tsuei, C.-Y., Kuo, T.-T., Huang, C.-T., Hsu, W.-M., Chung, Y.-H., Wu, H.-Y., Hsu, C.-C., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) "​Combinatorial targeting of MTHFD2 and PAICS in purine synthesis as a novel therapeutic strategy"​ //Cell Death & Disease// 10:786. 
 +  - Wu, P.-Y., Yu, I-S., Lin, Y.-C., Chang, Y.-T., Chen, C.-C., Lin, K.-H., Tseng, T.-H., Kargren, M., Tai, Y.-L., Shen, T.-L., Liu, Y.-L., Wang, B.-J., Chang, C.-H., Chen, W.-M., __**Juan, H.-F.**__, Huang, S.-F., Chan, Y.-Y., Liao, Y.-F., Hsu, W.-M., Lee, H. (2019"​Activation of aryl hydrocarbon receptor by kynurenine impairs progression and metastasis of neuroblastoma"​ //Cancer Research// 79(21):​5550-5562
 +  - Huang, C.-T., Hsieh, C.-H., Lee, W.-C., Liu, Y.-L., Yang, T.-S., Hsu, W.-M., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* ​(2019) ​"​Therapeutic targeting of non-oncogene dependencies in high-risk neuroblastoma"​ //Clinical Cancer Research// ​25(13):​4063-4078. 
 +  - Huang, C.-T., Hsieh, C.-H., Chung, Y.-H., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) "​Perturbational gene-expression signatures for combinatorial drug discovery"​ //​iScience//​ 15:291-306 (**Cell Press**).
   - Yang, T.-W., Sahu, D., Chang, Y.-W., Hsu, C.-L., Hsieh, C.-H., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) “RNA-binding proteomics reveals MATR3 interacting with lncRNA SNHG1 to enhance neuroblastoma progression” //Journal of Proteome Research// 18: 406–416.   - Yang, T.-W., Sahu, D., Chang, Y.-W., Hsu, C.-L., Hsieh, C.-H., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) “RNA-binding proteomics reveals MATR3 interacting with lncRNA SNHG1 to enhance neuroblastoma progression” //Journal of Proteome Research// 18: 406–416.
-  - Chang, J.-Y., Yu, W.-H., __**Juan, H.-F.**__*, Huang, H.-C.* (2018) "​Dynamics of alternative polyadenylation in human preimplantation embryos"​ //​Biochemical and Biophysical Research// ​Sep 11. pii: S0006-291X(18)31946-6.+  - Chang, J.-Y., Yu, W.-H., __**Juan, H.-F.**__*, Huang, H.-C.* (2018) "​Dynamics of alternative polyadenylation in human preimplantation embryos"​ //​Biochemical and Biophysical Research ​Communications// 504(4):727-733.
   - Huang, C.-T., Hsieh, C.-H., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2018) "A large-scale gene expression intensity-based similarity metric for drug repositioning"​ //​iScience//​ 7: 40-52. (Cell Press)   - Huang, C.-T., Hsieh, C.-H., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2018) "A large-scale gene expression intensity-based similarity metric for drug repositioning"​ //​iScience//​ 7: 40-52. (Cell Press)
   - Lin, M.-C., Chien, P.-H., Wu, H.-Y., Chen, S.-T., __**Juan, H.-F.**__, Lou, P.-J.*, Huang, M.-C. (2018) "​C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer"​ //​Oncogene//​ Jun 21. doi: 10.1038/​s41388-018-0375-0.   - Lin, M.-C., Chien, P.-H., Wu, H.-Y., Chen, S.-T., __**Juan, H.-F.**__, Lou, P.-J.*, Huang, M.-C. (2018) "​C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer"​ //​Oncogene//​ Jun 21. doi: 10.1038/​s41388-018-0375-0.
   - Sahu, D., Ho, S.-Y., __**Juan, H.-F.**__*, Huang, H.-C.* (2018) "​High-risk,​ expression-based prognostic long noncoding RNA signature in neuroblastoma"​ //JNCI Cancer Spectrum// 2(2): pky015.   - Sahu, D., Ho, S.-Y., __**Juan, H.-F.**__*, Huang, H.-C.* (2018) "​High-risk,​ expression-based prognostic long noncoding RNA signature in neuroblastoma"​ //JNCI Cancer Spectrum// 2(2): pky015.
-  - Cheng, A.-N., Fan, C.-C., Lo, Y.-K., Kuo, C.-L., Wang, H.-C., Lien, I-H., Lin, S.-Y., Chen, C.-H., Jiang, S. S., Chang, I-S., __**Juan, H.-F.**__, Lyu, P.-C., Lee, A Y.-L.* "​Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer"​ //​Scientific Reports// 7: 17024.+  - Cheng, A.-N., Fan, C.-C., Lo, Y.-K., Kuo, C.-L., Wang, H.-C., Lien, I-H., Lin, S.-Y., Chen, C.-H., Jiang, S. S., Chang, I-S., __**Juan, H.-F.**__, Lyu, P.-C., Lee, A Y.-L.* ​(2017) ​"​Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer"​ //​Scientific Reports// 7: 17024.
   - Cheung, H. Y. C., Hsu, C.-L., Chen, K.-P., Chong, S.-T., Huang, H.-C.*, __**Juan, H.-F.**__* (2017) "​MCM2-regulated functional networks in lung cancer by multi-dimensional proteomic approach"​ //​Scientific Reports// 7(1):13302.   - Cheung, H. Y. C., Hsu, C.-L., Chen, K.-P., Chong, S.-T., Huang, H.-C.*, __**Juan, H.-F.**__* (2017) "​MCM2-regulated functional networks in lung cancer by multi-dimensional proteomic approach"​ //​Scientific Reports// 7(1):13302.
   - Hsu, C.-L., Wang, J.-K., Lu, P.-C., Huang, H.-C.*, and __**Juan, H.-F.**__* (2017) "​DynaPho:​ a web platform for inferring the dynamics of time-series phosphoproteomics"​ //​Bioinformatics//​ 33(22):​3664-3666.   - Hsu, C.-L., Wang, J.-K., Lu, P.-C., Huang, H.-C.*, and __**Juan, H.-F.**__* (2017) "​DynaPho:​ a web platform for inferring the dynamics of time-series phosphoproteomics"​ //​Bioinformatics//​ 33(22):​3664-3666.
Line 114: Line 121:
   - __**Juan, H.-F.**__, Hung, C.-C., Wang, K.-T., Chiou, S.-H.* (1999) “Comparison of three classes of snake neurotoxins by homology modeling and computer simulation graphics.” Biochem Biophys Res Commun. 257: 500-510.   - __**Juan, H.-F.**__, Hung, C.-C., Wang, K.-T., Chiou, S.-H.* (1999) “Comparison of three classes of snake neurotoxins by homology modeling and computer simulation graphics.” Biochem Biophys Res Commun. 257: 500-510.
 ===== Conference Proceedings / 研討會論文 ===== ===== Conference Proceedings / 研討會論文 =====
 +  - Chang, H.-C., Huang, H.-C., __**Juan, H.-F.**__*, Hsu, C.-L* (2019) "​Investigating the role of super-enhancer RNAs underlying embryonic stem cell differentiation"​ //Joint 30th International Conference on Genome Informatics&​ Australasian Bioinformatics and Computational Biology Society (GIW/ABACBS 2019)//, Sydney, Australia, Dec. 9-11, 2019. (**Oral Presentation**)
 +  - Cheung, C.H.Y., Hsu, C.-L., Lin, T.-Y., Chen, W.-T., Wang, Y.-C., Huang, H.-C.*, and __**Juan, H.-F.**__* "​Quantitative Proteomics and Phosphoproteomics Analyses Reveal the Regulatory Roles of ZNF322A in lung cancer"​ //2019 Multiomics and precision medicine joint conference//,​ Tainan, Taiwan, Dec. 07-08, 2019. (**Young scientist oral presentation competition - 2nd place**)
 +  -  Lee, W.-H., Chen, K.-P., Wang, K., Huang, H.-C.*, and __**Juan, H.-F.**__* "​Characterizing the cancer-associated microbiome with small RNA sequencing data" //2019 Multiomics and precision medicine joint conference//,​ Tainan, Taiwan, Dec. 07-08, 2019. (**Poster Award**)
 +  -  Hsieh, C.-H., Cheung, C.H.-Y., Liu, Y.-L., Hou, C.-L., Hsu, C.-L., Huang, C.-T., Yang, T.-S., Chen, S.-F., Chen, C.-N., Hsu, W.-M.*, Huang, H.-C*. and __**Juan, H.-F.**__* "​Quantitative Proteomics of Th-MYCN Transgenic Mice Reveals Aurora Kinase Inhibitor Altered Metabolic Pathways and Enhanced ACADM To Suppress Neuroblastoma Progression"​ //2019 Multiomics and precision medicine joint conference//,​ Tainan, Taiwan, Dec. 07-08, 2019. (**Poster Award**)
 +  - Kao, Y.-C., Chang, N.-W., Lai, C.P., Huang, H.-C.*, and __**Juan, H.-F.**__* " The role of ectopic ATP synthase in cell-to-cell communication by extracellular vesicles"​ //2019 The Taiwan Society for Biochemistry and Molecular Autumn Camp//, New Taipei City, Taiwan, Nov. 15-17, 2019.
 +  - Chang, Y.-W., Hou, J.-T., Liaw, Y-g., Huang, T.-Y., Chen, M.-C., Yin, C.-F., Hung, Y.-H., Hsu, C.-L., Huang, H.-C.*, and __**Juan, H.-F.**__* "​Mitochondrial ATP synthase trafficking toward the cell surface depending on KIF5B and Drp1 to serve as a new target for overcoming chemoresistance"​ //2019 Annual Meeting of Taiwan Society for Mitochondrial Research and Medicine//, Taipei, Taiwan, Nov. 09, 2019. (**Honorable Award**)
 +  - Wang, W. H., Hsu, C. L., Huang, H.-C.*, and __**Juan, H.-F.**__* "​Cyclic stretch-induced biological functions by phosphoproteomics profiling"​ //2019 Annual Meeting of Taiwan Society for Mitochondrial Research and Medicine//, Taipei, Taiwan, Nov. 09, 2019. (**Honorable Award**)
 +  - __**Juan, H.-F.**__* and Huang, H.-C.* "​Targeting Trafficking of Mitochondrial Key Energy Protein for Cancer Therapy"​ //16th conference of The Asian Society for Mitochondrial Research and Medicine (ASMRM2019)//,​ Fukuoka city, Japan, Oct. 3-5, 2019 (**E-poster**)
 +  - Huang, C.-T., Hsieh, C.-H., Lee, W.-C., Liu, Y.-L., Yang, T.-S., Hsu, W.-M., Oyang, Y.-J., Huang, H.-C.* and __**Juan, H.-F.**__* "​Therapeutic targeting of non-oncogene dependencies in high-risk neuroblastoma " //The 78th Annual Meeting of the Japanese Cancer Association//,​ Kyoto, Japan, Sep. 26-28, 2019. (**Travel Grant Award**)
 +  - Hsieh, C.-H., Cheung, C. H. Y., Liu, Y.-L., Hou, C.-L., Hsu, C.-L., Huang, C.-T., Yang, T.-S., Chen, S.-F., Chen, C.-N., Hsu, W.-M.*, Huang, H.-C.* and __**Juan, H.-F.**__* "​Targeting aurora kinases reduces neuroblastoma progression by altering the metabolic pathways via enhancing ACADM" //The 78th Annual Meeting of the Japanese Cancer Association//,​ Kyoto, Japan, Sep. 26-28, 2019. (**Travel Grant Award**)
 +  - Kao, Y.-C., Chang, N.-W., Chang, Y.-W., Lai, C. P., Huang, H.-C. and __**Juan, H.-F.**__* "​Ectopic ATP synthase induces extracellular vesicle release for cell-to-cell communications"​ The 8th Congress of the International Society for Extracellular Vesicles (ISEV2019), Kyoto, Japan, April 24-28, 2019.
 +  - Wang, C.-C., Chang, Y.-W., Wu, C.-H., Cheung, C. H. Y., Lee, J.-L., Huang, H.-C.* and __**Juan, H.-F.**__* "​Mesenchymal stem cells-derived microenvironment promote lung cancer cell progression via c-Fos S374 phosphorylation in MAPK signaling pathway"​ //34th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 23-24, 2019. (**Best Poster Award**)
 +  - Tsai, H.-H., Wang, W.-H., Hou, J.-T., Hsieh, C.-H., Chang, Y.-W., Huang, H.-C.* and __**Juan, H.-F.**__* "​Investigation of molecular mechanism in mitochondria fission leading ATP synthase toward cell surface"​ //34th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 23-24, 2019. (**Best Poster Award**)
 +  - Yang, F.-M., Kuo, I.-Y., __**Juan, H.-F.**__, Wang, Y.-C.*. 2019 Rab37-mediated IL-6 secretion in the polarization of macrophages. The 34th joint annual conference of biomedical sciences. (**Best Poster Award**).
 +  - Lee, W.-H., Chen, K.-P., Huang, H.-C.* and __**Juan, H.-F.**__* "​Exploring cancer-associated microbiome characteristics using large-scale patient small RNA sequencing data" //34th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 23-24, 2019.
 +  - Chang, N.-W., Kao, Y.-C., Chang, Y.-W., Lai, C. P., Huang, H.-C.* and __**Juan, H.-F.**__* "The function of ectopic ATP synthase in extracellular vesicles under serum deprivation"​ //34th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 23-24, 2019.
 +  - Liaw, Y-g., Chang, Y.-W., Hung, Y.-H., Huang, H.-C.* and __**Juan, H.-F.**__* "​Live-cell imaging of ectopic ATP synthase trafficking"​ //34th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 23-24, 2019.
   - Cheung, H. Y. C., Hsu, C.-L., Tsuei, C.-Y., Kuo, T.-T., Huang, C.-T., Wu, H.-Y., Hsu, C.-C. Chung, Y.-H., Huang, H.-C.* and __**Juan, H.-F.**__* "​MYCN-mediated purine biosynthesis enhances cancer metabolism via MTHFD2 and PAICS in neuroblastoma"​ //2017 Taiwan Proteomics Society (TPS) Annual Meeting//, Taichung, Taiwan, Nov. 17, 2018. (**1st Prize Poster Award**)   - Cheung, H. Y. C., Hsu, C.-L., Tsuei, C.-Y., Kuo, T.-T., Huang, C.-T., Wu, H.-Y., Hsu, C.-C. Chung, Y.-H., Huang, H.-C.* and __**Juan, H.-F.**__* "​MYCN-mediated purine biosynthesis enhances cancer metabolism via MTHFD2 and PAICS in neuroblastoma"​ //2017 Taiwan Proteomics Society (TPS) Annual Meeting//, Taichung, Taiwan, Nov. 17, 2018. (**1st Prize Poster Award**)
   - Wang, W.-H., Hsu, C.-L., Huang, H.-C.* and __**Juan, H.-F.**__* "​Phosphoproteomics reveals cyclic stretch induces microtubule rearrangement,​ changes cell alignment and disrupts mitochondrial dynamics in lung cells" //2018 The Taiwan Society for Biochemistry and Molecular Autumn Camp//, Chitou, Taiwan, Nov. 9-11, 2018.   - Wang, W.-H., Hsu, C.-L., Huang, H.-C.* and __**Juan, H.-F.**__* "​Phosphoproteomics reveals cyclic stretch induces microtubule rearrangement,​ changes cell alignment and disrupts mitochondrial dynamics in lung cells" //2018 The Taiwan Society for Biochemistry and Molecular Autumn Camp//, Chitou, Taiwan, Nov. 9-11, 2018.
Line 342: Line 366:
   - Chiou, S.-H., __**Juan, H.-F.**__ and Huang, H.-C. (1995) “Octopus S-crystallins with endogenous glutathione S-transferase activity: computer graphic modelling and sequence comparison with authentic enzymes.” (Abstract#​619-M) 9th Symposium of the Protein Society, Boston, MA, U. S. A., July 8-12.   - Chiou, S.-H., __**Juan, H.-F.**__ and Huang, H.-C. (1995) “Octopus S-crystallins with endogenous glutathione S-transferase activity: computer graphic modelling and sequence comparison with authentic enzymes.” (Abstract#​619-M) 9th Symposium of the Protein Society, Boston, MA, U. S. A., July 8-12.
 ===== Books (Chapters) / 專書(章節) ===== ===== Books (Chapters) / 專書(章節) =====
 +  - __**Juan, H.-F.**__ (2019) "​Proteomic techniques and their applications"​ in Biomolecular and Bioanalytical Techniques: Theory, Methodology and Applications,​ Edited by Vasudevan Ramesh (John Wiley & Sons, Inc., UK), pp.81-99.
 +  - Siddiqui, H., Sami, F., __**Juan, H.-F.**__* and Hayat, S.* (2019) "​Brassinosteroid Regulated Physiological Process: An Omics Perspective"​ Brassinosteroids:​ Plant Growth and Development,​ ed. By Shamsul Hayat, Dr. Mohammad Yusuf, Dr. Renu Bhardwaj & Dr. Andrzej Bajguz (Springer Nature, Singapore), pp. 297-322.
   - __**Juan, H.-F.**__ and Huang, H.-C. (2018) A Practical Guide to Cancer Systems Biology (World Scientific Publishing, Singapore)   - __**Juan, H.-F.**__ and Huang, H.-C. (2018) A Practical Guide to Cancer Systems Biology (World Scientific Publishing, Singapore)
 +  - __**Juan, H.-F.**__ (2017) "Data Sources for herbal and traditional medicines"​ in Computational Systems Pharmacology and Toxicology, Edited by Dale Johnson and Rudy J Richardson (The Royal Society of Chemistry, Cambridge, UK), pp. 243-260.
   - __**Juan, H.-F.**__ and Huang, H.-C. (2012) Systems Biology: Applications in cancer-related research (World Scientific Publishing, Singapore).   - __**Juan, H.-F.**__ and Huang, H.-C. (2012) Systems Biology: Applications in cancer-related research (World Scientific Publishing, Singapore).
   - __**Juan, H.-F.**__ (2011) "​Transcriptomics and proteomics study in regulation of brassinosteroids"​ in Brassinosteroids:​ A Class of Plant Hormone, ed. Shamsul Hayat and Aqil Ahmad (Springer, Netherlands),​ pp. 393-402.   - __**Juan, H.-F.**__ (2011) "​Transcriptomics and proteomics study in regulation of brassinosteroids"​ in Brassinosteroids:​ A Class of Plant Hormone, ed. Shamsul Hayat and Aqil Ahmad (Springer, Netherlands),​ pp. 393-402.