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publication:juan [2019/05/29 19:30]
游文萱
publication:juan [2020/06/13 14:49] (current)
游文萱
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 ===== Journal Papers / 期刊論文 ===== ===== Journal Papers / 期刊論文 =====
-  ​Huang, C.-T., ​Hsieh, C.-H., ​ChungY.-H., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) "Perturbational gene-expression signatures for combinatorial drug discovery" //iScience// (**Cell Press**, doi: 10.1016/j.isci.2019.04.039). +  
-  - Huang, C.-T., Hsieh, C.-H., Lee, W.-C., Liu, Y.-L., Yang, T.-S., Hsu, W.-M., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* "​Therapeutic targeting of non-oncogene dependencies in high-risk neuroblastoma"​ //Clinical Cancer Research// (Accepted).+  ​Cheung, H. Y. C., Hsu, C.-L., Lin, T.-Y., ChenW.-T., Wang, Y.-C., Huang, H.-C.*, __**Juan, ​H.-F.**__* (2020) "​ZNF322A-mediated protein phosphorylation induces autophagosome formation through modulation of IRS1-AKT glucose uptake and HSP-elicited UPR in lung cancer” //Journal of Biomedical Science// (in press). 
 +  - WangW.-H.Hsu, C.-L., Huang, ​H.-C.*__**Juan, H.-F.**__* (2020) "​Quantitative phosphoproteomics reveals cell alignment and mitochondrial length change under cyclic stretching in lung cells" //​International Journal of Molecular Sciences// 21(11):​E4074. 
 +  - Yin, C.-F., Kao, S.-C., Hsu, C.-L., Cheung, C. H.Y., Chang, Y.-W., Huang, H.-C.*, __**Juan, H.-F.**__* (2020) "Phosphoproteome analysis reveals dynamic heat shock protein 27 phosphorylation in tanshinone IIA-induced cell death" //Journal of Proteome Research// 19(4):​1620-1634. 
 +  - Lee, P.-C. Chen, S.-T., Kuo, T.-C., Lin, T.-C., Lin, M.-C., Huang, J., Hung, J.-S., Hsu, C.-L., __**Juan, H.-F.**__Lee, P.-H., and Huang, M.-C. (2020) "​C1GALT1 is associated with poor survival and promotes soluble Ephrin A1-mediated cell migration through activation of EPHA2 in gastric cancer"​ //​Oncogene//​ 39(13):2724-2740. 
 +  - Lee, W.-H., Chen, K.-P., Wang, K., Huang, H.-C.*, __**Juan, H.-F.**__* (2020) "​Characterizing the cancer-associated microbiome with small RNA sequencing data" //​Biochemical and Biophysical Research Communications//​ 522:​776-782. 
 +  - Chang, H.-C., Huang, H.-C., __**Juan, H.-F.**__*, Hsu, C.-L* (2019) "​Investigating the role of super-enhancer RNAs underlying embryonic stem cell differentiation"​ //BMC Genomics// 20(Suppl ​10):896. 
 +  - Hsieh, C.-H., Cheung, C. H. Y., Liu, Y.-L., Hou, C.-L., Hsu, C.-L., Huang, C.-T., Yang, T.-S., Chen, S.-F., Chen, C.-N., Hsu, W.-M.*, Huang, H.-C.*, __**Juan, H.-F.**__* (2019) "​Quantitative proteomics of Th-MYCN transgenic mice reveals aurora kinase inhibitor altered metabolic pathways and enhanced ACADM to suppress neuroblastoma progression" ​//Journal of Proteome Research// 18(11):​3850-3866. 
 +  - Cheung, HY. C., Hsu, C.-L., Tsuei, C.-Y., Kuo, T.-T., Huang, C.-T., Hsu, W.-M., Chung, Y.-H., Wu, H.-Y., Hsu, C.-C., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) "​Combinatorial targeting of MTHFD2 and PAICS in purine synthesis as a novel therapeutic strategy"​ //Cell Death & Disease// 10:786. 
 +  - Wu, P.-Y., Yu, I-S., Lin, Y.-C., Chang, Y.-T., Chen, C.-C., Lin, K.-H., Tseng, T.-H., Kargren, M., Tai, Y.-L., Shen, T.-L., Liu, Y.-L., Wang, B.-J., Chang, C.-H., Chen, W.-M., __**Juan, H.-F.**__, Huang, S.-F., Chan, Y.-Y., Liao, Y.-F., Hsu, W.-M., Lee, H. (2019"​Activation of aryl hydrocarbon receptor by kynurenine impairs progression and metastasis of neuroblastoma"​ //Cancer Research// 79(21):​5550-5562
 +  - Huang, C.-T., Hsieh, C.-H., Lee, W.-C., Liu, Y.-L., Yang, T.-S., Hsu, W.-M., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* ​(2019) ​"​Therapeutic targeting of non-oncogene dependencies in high-risk neuroblastoma"​ //Clinical Cancer Research// ​25(13):​4063-4078. 
 +  - Huang, C.-T., Hsieh, C.-H., Chung, Y.-H., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) "​Perturbational gene-expression signatures for combinatorial drug discovery"​ //​iScience//​ 15:291-306 (**Cell Press**).
   - Yang, T.-W., Sahu, D., Chang, Y.-W., Hsu, C.-L., Hsieh, C.-H., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) “RNA-binding proteomics reveals MATR3 interacting with lncRNA SNHG1 to enhance neuroblastoma progression” //Journal of Proteome Research// 18: 406–416.   - Yang, T.-W., Sahu, D., Chang, Y.-W., Hsu, C.-L., Hsieh, C.-H., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) “RNA-binding proteomics reveals MATR3 interacting with lncRNA SNHG1 to enhance neuroblastoma progression” //Journal of Proteome Research// 18: 406–416.
-  - Chang, J.-Y., Yu, W.-H., __**Juan, H.-F.**__*, Huang, H.-C.* (2018) "​Dynamics of alternative polyadenylation in human preimplantation embryos"​ //​Biochemical and Biophysical Research// ​Sep 11. pii: S0006-291X(18)31946-6.+  - Chang, J.-Y., Yu, W.-H., __**Juan, H.-F.**__*, Huang, H.-C.* (2018) "​Dynamics of alternative polyadenylation in human preimplantation embryos"​ //​Biochemical and Biophysical Research ​Communications// 504(4):727-733.
   - Huang, C.-T., Hsieh, C.-H., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2018) "A large-scale gene expression intensity-based similarity metric for drug repositioning"​ //​iScience//​ 7: 40-52. (Cell Press)   - Huang, C.-T., Hsieh, C.-H., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2018) "A large-scale gene expression intensity-based similarity metric for drug repositioning"​ //​iScience//​ 7: 40-52. (Cell Press)
   - Lin, M.-C., Chien, P.-H., Wu, H.-Y., Chen, S.-T., __**Juan, H.-F.**__, Lou, P.-J.*, Huang, M.-C. (2018) "​C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer"​ //​Oncogene//​ Jun 21. doi: 10.1038/​s41388-018-0375-0.   - Lin, M.-C., Chien, P.-H., Wu, H.-Y., Chen, S.-T., __**Juan, H.-F.**__, Lou, P.-J.*, Huang, M.-C. (2018) "​C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer"​ //​Oncogene//​ Jun 21. doi: 10.1038/​s41388-018-0375-0.
   - Sahu, D., Ho, S.-Y., __**Juan, H.-F.**__*, Huang, H.-C.* (2018) "​High-risk,​ expression-based prognostic long noncoding RNA signature in neuroblastoma"​ //JNCI Cancer Spectrum// 2(2): pky015.   - Sahu, D., Ho, S.-Y., __**Juan, H.-F.**__*, Huang, H.-C.* (2018) "​High-risk,​ expression-based prognostic long noncoding RNA signature in neuroblastoma"​ //JNCI Cancer Spectrum// 2(2): pky015.
-  - Cheng, A.-N., Fan, C.-C., Lo, Y.-K., Kuo, C.-L., Wang, H.-C., Lien, I-H., Lin, S.-Y., Chen, C.-H., Jiang, S. S., Chang, I-S., __**Juan, H.-F.**__, Lyu, P.-C., Lee, A Y.-L.* "​Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer"​ //​Scientific Reports// 7: 17024.+  - Cheng, A.-N., Fan, C.-C., Lo, Y.-K., Kuo, C.-L., Wang, H.-C., Lien, I-H., Lin, S.-Y., Chen, C.-H., Jiang, S. S., Chang, I-S., __**Juan, H.-F.**__, Lyu, P.-C., Lee, A Y.-L.* ​(2017) ​"​Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer"​ //​Scientific Reports// 7: 17024.
   - Cheung, H. Y. C., Hsu, C.-L., Chen, K.-P., Chong, S.-T., Huang, H.-C.*, __**Juan, H.-F.**__* (2017) "​MCM2-regulated functional networks in lung cancer by multi-dimensional proteomic approach"​ //​Scientific Reports// 7(1):13302.   - Cheung, H. Y. C., Hsu, C.-L., Chen, K.-P., Chong, S.-T., Huang, H.-C.*, __**Juan, H.-F.**__* (2017) "​MCM2-regulated functional networks in lung cancer by multi-dimensional proteomic approach"​ //​Scientific Reports// 7(1):13302.
   - Hsu, C.-L., Wang, J.-K., Lu, P.-C., Huang, H.-C.*, and __**Juan, H.-F.**__* (2017) "​DynaPho:​ a web platform for inferring the dynamics of time-series phosphoproteomics"​ //​Bioinformatics//​ 33(22):​3664-3666.   - Hsu, C.-L., Wang, J.-K., Lu, P.-C., Huang, H.-C.*, and __**Juan, H.-F.**__* (2017) "​DynaPho:​ a web platform for inferring the dynamics of time-series phosphoproteomics"​ //​Bioinformatics//​ 33(22):​3664-3666.
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   - __**Juan, H.-F.**__, Hung, C.-C., Wang, K.-T., Chiou, S.-H.* (1999) “Comparison of three classes of snake neurotoxins by homology modeling and computer simulation graphics.” Biochem Biophys Res Commun. 257: 500-510.   - __**Juan, H.-F.**__, Hung, C.-C., Wang, K.-T., Chiou, S.-H.* (1999) “Comparison of three classes of snake neurotoxins by homology modeling and computer simulation graphics.” Biochem Biophys Res Commun. 257: 500-510.
 ===== Conference Proceedings / 研討會論文 ===== ===== Conference Proceedings / 研討會論文 =====
 +  - Chang, H.-C., Huang, H.-C., __**Juan, H.-F.**__*, Hsu, C.-L* (2019) "​Investigating the role of super-enhancer RNAs underlying embryonic stem cell differentiation"​ //Joint 30th International Conference on Genome Informatics&​ Australasian Bioinformatics and Computational Biology Society (GIW/ABACBS 2019)//, Sydney, Australia, Dec. 9-11, 2019. (**Oral Presentation**)
 +  - Cheung, C.H.Y., Hsu, C.-L., Lin, T.-Y., Chen, W.-T., Wang, Y.-C., Huang, H.-C.*, and __**Juan, H.-F.**__* "​Quantitative Proteomics and Phosphoproteomics Analyses Reveal the Regulatory Roles of ZNF322A in lung cancer"​ //2019 Multiomics and precision medicine joint conference//,​ Tainan, Taiwan, Dec. 07-08, 2019. (**Young scientist oral presentation competition - 2nd place**)
 +  -  Lee, W.-H., Chen, K.-P., Wang, K., Huang, H.-C.*, and __**Juan, H.-F.**__* "​Characterizing the cancer-associated microbiome with small RNA sequencing data" //2019 Multiomics and precision medicine joint conference//,​ Tainan, Taiwan, Dec. 07-08, 2019. (**Poster Award**)
 +  -  Hsieh, C.-H., Cheung, C.H.-Y., Liu, Y.-L., Hou, C.-L., Hsu, C.-L., Huang, C.-T., Yang, T.-S., Chen, S.-F., Chen, C.-N., Hsu, W.-M.*, Huang, H.-C*. and __**Juan, H.-F.**__* "​Quantitative Proteomics of Th-MYCN Transgenic Mice Reveals Aurora Kinase Inhibitor Altered Metabolic Pathways and Enhanced ACADM To Suppress Neuroblastoma Progression"​ //2019 Multiomics and precision medicine joint conference//,​ Tainan, Taiwan, Dec. 07-08, 2019. (**Poster Award**)
 +  - Kao, Y.-C., Chang, N.-W., Lai, C.P., Huang, H.-C.*, and __**Juan, H.-F.**__* " The role of ectopic ATP synthase in cell-to-cell communication by extracellular vesicles"​ //2019 The Taiwan Society for Biochemistry and Molecular Autumn Camp//, New Taipei City, Taiwan, Nov. 15-17, 2019.
 +  - Chang, Y.-W., Hou, J.-T., Liaw, Y-g., Huang, T.-Y., Chen, M.-C., Yin, C.-F., Hung, Y.-H., Hsu, C.-L., Huang, H.-C.*, and __**Juan, H.-F.**__* "​Mitochondrial ATP synthase trafficking toward the cell surface depending on KIF5B and Drp1 to serve as a new target for overcoming chemoresistance"​ //2019 Annual Meeting of Taiwan Society for Mitochondrial Research and Medicine//, Taipei, Taiwan, Nov. 09, 2019. (**Honorable Award**)
 +  - Wang, W. H., Hsu, C. L., Huang, H.-C.*, and __**Juan, H.-F.**__* "​Cyclic stretch-induced biological functions by phosphoproteomics profiling"​ //2019 Annual Meeting of Taiwan Society for Mitochondrial Research and Medicine//, Taipei, Taiwan, Nov. 09, 2019. (**Honorable Award**)
 +  - __**Juan, H.-F.**__* and Huang, H.-C.* "​Targeting Trafficking of Mitochondrial Key Energy Protein for Cancer Therapy"​ //16th conference of The Asian Society for Mitochondrial Research and Medicine (ASMRM2019)//,​ Fukuoka city, Japan, Oct. 3-5, 2019 (**E-poster**)
 +  - Huang, C.-T., Hsieh, C.-H., Lee, W.-C., Liu, Y.-L., Yang, T.-S., Hsu, W.-M., Oyang, Y.-J., Huang, H.-C.* and __**Juan, H.-F.**__* "​Therapeutic targeting of non-oncogene dependencies in high-risk neuroblastoma " //The 78th Annual Meeting of the Japanese Cancer Association//,​ Kyoto, Japan, Sep. 26-28, 2019. (**Travel Grant Award**)
 +  - Hsieh, C.-H., Cheung, C. H. Y., Liu, Y.-L., Hou, C.-L., Hsu, C.-L., Huang, C.-T., Yang, T.-S., Chen, S.-F., Chen, C.-N., Hsu, W.-M.*, Huang, H.-C.* and __**Juan, H.-F.**__* "​Targeting aurora kinases reduces neuroblastoma progression by altering the metabolic pathways via enhancing ACADM" //The 78th Annual Meeting of the Japanese Cancer Association//,​ Kyoto, Japan, Sep. 26-28, 2019. (**Travel Grant Award**)
 +  - Kao, Y.-C., Chang, N.-W., Chang, Y.-W., Lai, C. P., Huang, H.-C. and __**Juan, H.-F.**__* "​Ectopic ATP synthase induces extracellular vesicle release for cell-to-cell communications"​ The 8th Congress of the International Society for Extracellular Vesicles (ISEV2019), Kyoto, Japan, April 24-28, 2019.
 +  - Wang, C.-C., Chang, Y.-W., Wu, C.-H., Cheung, C. H. Y., Lee, J.-L., Huang, H.-C.* and __**Juan, H.-F.**__* "​Mesenchymal stem cells-derived microenvironment promote lung cancer cell progression via c-Fos S374 phosphorylation in MAPK signaling pathway"​ //34th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 23-24, 2019. (**Best Poster Award**)
 +  - Tsai, H.-H., Wang, W.-H., Hou, J.-T., Hsieh, C.-H., Chang, Y.-W., Huang, H.-C.* and __**Juan, H.-F.**__* "​Investigation of molecular mechanism in mitochondria fission leading ATP synthase toward cell surface"​ //34th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 23-24, 2019. (**Best Poster Award**)
 +  - Yang, F.-M., Kuo, I.-Y., __**Juan, H.-F.**__, Wang, Y.-C.*. 2019 Rab37-mediated IL-6 secretion in the polarization of macrophages. The 34th joint annual conference of biomedical sciences. (**Best Poster Award**).
 +  - Lee, W.-H., Chen, K.-P., Huang, H.-C.* and __**Juan, H.-F.**__* "​Exploring cancer-associated microbiome characteristics using large-scale patient small RNA sequencing data" //34th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 23-24, 2019.
 +  - Chang, N.-W., Kao, Y.-C., Chang, Y.-W., Lai, C. P., Huang, H.-C.* and __**Juan, H.-F.**__* "The function of ectopic ATP synthase in extracellular vesicles under serum deprivation"​ //34th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 23-24, 2019.
 +  - Liaw, Y-g., Chang, Y.-W., Hung, Y.-H., Huang, H.-C.* and __**Juan, H.-F.**__* "​Live-cell imaging of ectopic ATP synthase trafficking"​ //34th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 23-24, 2019.
   - Cheung, H. Y. C., Hsu, C.-L., Tsuei, C.-Y., Kuo, T.-T., Huang, C.-T., Wu, H.-Y., Hsu, C.-C. Chung, Y.-H., Huang, H.-C.* and __**Juan, H.-F.**__* "​MYCN-mediated purine biosynthesis enhances cancer metabolism via MTHFD2 and PAICS in neuroblastoma"​ //2017 Taiwan Proteomics Society (TPS) Annual Meeting//, Taichung, Taiwan, Nov. 17, 2018. (**1st Prize Poster Award**)   - Cheung, H. Y. C., Hsu, C.-L., Tsuei, C.-Y., Kuo, T.-T., Huang, C.-T., Wu, H.-Y., Hsu, C.-C. Chung, Y.-H., Huang, H.-C.* and __**Juan, H.-F.**__* "​MYCN-mediated purine biosynthesis enhances cancer metabolism via MTHFD2 and PAICS in neuroblastoma"​ //2017 Taiwan Proteomics Society (TPS) Annual Meeting//, Taichung, Taiwan, Nov. 17, 2018. (**1st Prize Poster Award**)
   - Wang, W.-H., Hsu, C.-L., Huang, H.-C.* and __**Juan, H.-F.**__* "​Phosphoproteomics reveals cyclic stretch induces microtubule rearrangement,​ changes cell alignment and disrupts mitochondrial dynamics in lung cells" //2018 The Taiwan Society for Biochemistry and Molecular Autumn Camp//, Chitou, Taiwan, Nov. 9-11, 2018.   - Wang, W.-H., Hsu, C.-L., Huang, H.-C.* and __**Juan, H.-F.**__* "​Phosphoproteomics reveals cyclic stretch induces microtubule rearrangement,​ changes cell alignment and disrupts mitochondrial dynamics in lung cells" //2018 The Taiwan Society for Biochemistry and Molecular Autumn Camp//, Chitou, Taiwan, Nov. 9-11, 2018.
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   - Chiou, S.-H., __**Juan, H.-F.**__ and Huang, H.-C. (1995) “Octopus S-crystallins with endogenous glutathione S-transferase activity: computer graphic modelling and sequence comparison with authentic enzymes.” (Abstract#​619-M) 9th Symposium of the Protein Society, Boston, MA, U. S. A., July 8-12.   - Chiou, S.-H., __**Juan, H.-F.**__ and Huang, H.-C. (1995) “Octopus S-crystallins with endogenous glutathione S-transferase activity: computer graphic modelling and sequence comparison with authentic enzymes.” (Abstract#​619-M) 9th Symposium of the Protein Society, Boston, MA, U. S. A., July 8-12.
 ===== Books (Chapters) / 專書(章節) ===== ===== Books (Chapters) / 專書(章節) =====
 +  - __**Juan, H.-F.**__ (2019) "​Proteomic techniques and their applications"​ in Biomolecular and Bioanalytical Techniques: Theory, Methodology and Applications,​ Edited by Vasudevan Ramesh (John Wiley & Sons, Inc., UK), pp.81-99.
 +  - Siddiqui, H., Sami, F., __**Juan, H.-F.**__* and Hayat, S.* (2019) "​Brassinosteroid Regulated Physiological Process: An Omics Perspective"​ Brassinosteroids:​ Plant Growth and Development,​ ed. By Shamsul Hayat, Dr. Mohammad Yusuf, Dr. Renu Bhardwaj & Dr. Andrzej Bajguz (Springer Nature, Singapore), pp. 297-322.
   - __**Juan, H.-F.**__ and Huang, H.-C. (2018) A Practical Guide to Cancer Systems Biology (World Scientific Publishing, Singapore)   - __**Juan, H.-F.**__ and Huang, H.-C. (2018) A Practical Guide to Cancer Systems Biology (World Scientific Publishing, Singapore)
 +  - __**Juan, H.-F.**__ (2017) "Data Sources for herbal and traditional medicines"​ in Computational Systems Pharmacology and Toxicology, Edited by Dale Johnson and Rudy J Richardson (The Royal Society of Chemistry, Cambridge, UK), pp. 243-260.
   - __**Juan, H.-F.**__ and Huang, H.-C. (2012) Systems Biology: Applications in cancer-related research (World Scientific Publishing, Singapore).   - __**Juan, H.-F.**__ and Huang, H.-C. (2012) Systems Biology: Applications in cancer-related research (World Scientific Publishing, Singapore).
   - __**Juan, H.-F.**__ (2011) "​Transcriptomics and proteomics study in regulation of brassinosteroids"​ in Brassinosteroids:​ A Class of Plant Hormone, ed. Shamsul Hayat and Aqil Ahmad (Springer, Netherlands),​ pp. 393-402.   - __**Juan, H.-F.**__ (2011) "​Transcriptomics and proteomics study in regulation of brassinosteroids"​ in Brassinosteroids:​ A Class of Plant Hormone, ed. Shamsul Hayat and Aqil Ahmad (Springer, Netherlands),​ pp. 393-402.