喜愛數理、資訊和生物三角關係的理科女

如何成為跨領域科學家的心路歷程

Hsueh-Fen Juan ( 阮雪芬; Yuki )

Dr. Hsueh-Fen Juan was born in 1969, Miao-Li, Taiwan. She received her BS and MS degree in Botany and PhD in Biochemical Sciences from National Taiwan University (NTU) in 1999. She worked as a research scientist in the Japan International Research Center for Agricultural Sciences (Tsukuba, Japan) during 2000-2001 and a postdoctoral research fellow in the Institute of Biological Chemistry, Academia Sinica (Taipei, Taiwan) during 2001-2002. She started her academic career in the Department of Chemical Engineering, National Taipei University of Technology as an assistant professor and in the Department of Computer Science and Information Engineering at NTU as an adjunct assistant professor in 2002. She moved to NTU in 2004 as an assistant professor in the Department of Life Science and the Institute of Molecular and Cellular Biology. She was promoted to be the associate professor in 2006 and full professor in 2009 in the Department of Life Science, Institute of Molecular and Cellular Biology and Graduate Institute of Biomedical Electronics and Bioinformatics, NTU. Dr. Juan studied synthetic biology with Professor Hirotada Mori (NIST, Japan) in 2006 and Dr. James C. Liao (UCLA, USA) during 2007-2008. She is currently working on synthetic biology and systems biology by integrating genomics, transcriptomics, proteomics and bioinformatics for molecular signaling as well as biomarker and drug discovery.

Prof. Juan has developed a number of novel methods to advance systems-biology research and applied such approach for drug discovery and elucidating molecular mechanism of drug responses in cancer cells. She has published more than 100 journal papers. Among these publications, Prof. Juan has breakthrough research achievement in targeting ectopic ATP synthase for cancer therapy, therefore Science Daily & American Chemical Society weekly news reported these results; additionally, she has two papers selecting as ESI highly cited papers in 2013. She is now the editor board of Scientific Reports (Nature Publishing Group). Since Dr. Juan made significant contributions through systems biology approach to development of methodology and cancer therapy; she received the awards “Taiwan's Ten Outstanding Young Persons” (2008), FY2011 JSPS Invitation Fellowship Program for Research in Japan (2011), K. T. Li Breakthrough Award by Institute of Information and Computing Machinery (2012), and National Science Council (NSC) Award for Special Talents of the Colleges (2010-2015), NTU Academic Performance Reward (2015, 2016) and 2015 USA Emerging Information and Technology Association (EITA) Service Award. Additionally, she has been invited to give more than 140 talks worldwide and leads her team members to obtain more than 72 research awards.

Professor

  • Department of Life Science,
  • Institute of Molecular & Cellular Biology,
  • Institute of Biomedical Electronics & Bioinformatics,
  • Genome and Systems Biology Degree Program,
  • Center for Systems Biology and Bioinformatics,
  • National Taiwan University, Taipei, Taiwan
  • CV in PDF (November, 2017)

Research

  • Systems biology
  • Proteomics
  • Bioinformatics
  • Transcriptomics
  • Synthetic biology
  • Cancer biology
  • Drug discovery
  • Bioenergy

Education

  • 1994-1999 Ph.D., molecular modeling & protein chemistry
    • (advisers: Kung-Tsung Wang & Shyh-Horng Chiou)
    • Graduate Institute of Biochemical Sciences, National Taiwan University, Taiwan
  • 1992-1994 M.S., plant physiology
    • (adviser: Yih-Ming Chen) Graduate Institute of Botany, National Taiwan University, Taiwan
  • 1988-1992 B.S., botany
    • Department of Botany, National Taiwan University, Taiwan

Honors and Awards

  • 2017-2018 Ministry of Science and Technology (MOST) Award for Special Talents of the Colleges
  • 2015 Emerging Information and Technology Association (EITA) Service Award (USA)
  • 2015 NTU Academic Performance Reward
  • 2010-2015 Ministry of Science and Technology (MOST)/National Science Council (NSC) Award for Special Talents of the Colleges
  • 2012 K. T. Li Breakthrough Award by Institute of Information and Computing Machinery
  • 2012 The Ph.D. Dissertation Advisor Award by Institute of Information and Computing Machinery
  • 2011 Japan Society for the Promotion of Science (JSPS) Fellowship
  • 2010-2013, National Science Council (NSC) Award for Special Talents of the Colleges
  • 2008 Taiwan's Ten Outstanding Young Persons
  • 2010 NTU Excellent Paper Award
  • 2006~2009, 2011~2012 NTU Distinguish Paper Award
  • 2007 National Science Council Foreign Short Term Research Fellowship
  • 2006 Ministry of Education (MOE) Overseas Research Fellowship
  • 1999 Selected Oral Presentation in 14th Joint Annual Conference of Biomedical Sciences
  • 1993 The membership in The Phi Tau Phi Scholastic Honor Society
  • 1992-1994 Ministry of Education (MOE) Top 10% Excellent Master Student Scholarship
  • 1992 Certificate in “Multi-Dimensional NMR Spectroscopy in Solution”, Academia Sinica
  • 1991-1992 The Chung-Cheng Scholarship
  • 1992 The 1st Place at Department of Botany, NTU, Taiwan
  • 1989-1992 National Taiwan University Presidential Award
  • 1989-1992 The Scholarship for Talented Students in Mathematics and Natural Science
  • 1988-1989 The Bursary and Excellence Scholarship
  • 1989 The Thoughts of Dr. Sun Yat-Sen Scholarship
  • 1985-1987 Talented Students in the Training Program for Biological Science in Academia Sinica
  • 1985-1988 Talented Students in Mathematics Class of Taipei Municipal First Girls' Senior High School

Professional Experiences

  • 2015/05-now
    • Editorial Board, Scientific Reports (Nature Publishing Group)
  • 2009/08-now
    • Professor, Department of Life Science, Institute of Molecular and Cellular Biology and Graduate Institute of Biomedical Electronics and Bioinformatics, NTU, Taiwan
  • 2015/08-2017/7
    • Convener, Graduate Institute of Biomedical Electronics and Bioinformatics
  • 2008/08-2009/12
    • Leader of Technology Service Group, Center for Biotechnology, NTU, Taiwan
  • 2006/08-2009/07
    • Associate Professor, Department of Life Science, Institute of Molecular and Cellular Biology and Graduate Institute of Biomedical Electronics and Bioinformatics, NTU, Taiwan
  • 2007/08-2008/02
    • Visiting Scholar, Department of Chemical & Biomolecular Engineering, University of California, Los Angeles, USA (Dr. James Liao's Laboratory)
  • 2006/06-2007/02
    • Deputy Director Center for Systems Biology and Bioinformatics, National Taiwan University
  • 2006/08-2009/07
    • Associate Professor, Department of Life Science, Institute of Molecular & Cellular Biology, National Taiwan University
  • 2006/07-2006/08
    • Visiting Professor, Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara, Japan (Dr. Hirotada Mori's Laboratory)
  • 2004/08-2006/07
    • Assistant Professor, Department of Life Science, Institute of Molecular & Cellular Biology, National Taiwan University
  • 2002/08-2004/07
    • Assistant Professor, Department of Chemical Engineering, National Taipei University of Technology
  • 2001/08-2002/07
    • Postdoctoral Fellow, Institute of Biological Chemistry, Academia Sinica, Taiwan
  • 2001/04-2001/07
    • Research Associate, Division of Bioresource, Japan International Research Center for Agricultural Sciences, Tsukuba, Japan
  • 2000/08-2001/03
    • Research Assistant, Division of Bioresource, Japan International Research Center for Agricultural Sciences, Japan