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publication:juan [2019/11/25 07:36] 游文萱 [Journal Papers / 期刊論文] |
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===== Journal Papers / 期刊論文 ===== | ===== Journal Papers / 期刊論文 ===== | ||
- | - Lee, W.-H., Chen, K.-P., Wang, K., Huang, H.-C.*, __**Juan, H.-F.**__* "Characterizing the cancer-associated microbiome with small RNA sequencing data" //Biochemical and Biophysical Research Communications// (Accepted). | + | |
- | - Cheung, H. Y. C., Hsu, C.-L., Tsuei, C.-Y., Kuo, T.-T., Huang, C.-T., Hsu, W.-M., Chung, Y.-H., Wu, H.-Y., Hsu, C.-C., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) "Combinatorial targeting of MTHFD2 and PAICS in purine synthesis as a novel therapeutic strategy" //Cell Death and Disease// (Accepted). | + | - Wang, W.-H., Kao, Y.-C., Hsieh, C.-H., Tsai, S.-Y., Y. Cheung, C. H., Huang, H.-C.*, __**Juan, H.-F.**__* (2024) "Multiomics reveals induction of neuroblastoma SK-N-BE(2)C cell death by Mitochondrial Division Inhibitor 1 (Mdivi-1) through multiple effects" //Journal of Proteome Research// 23(1):301-315. |
- | - Hsieh, C.-H., Cheung, C. H. Y., Liu, Y.-L., Hou, C.-L., Hsu, C.-L., Huang, C.-T., Yang, T.-S., Chen, S.-F., Chen, C.-N., Hsu, W.-M.*, Huang, H.-C.*, __**Juan, H.-F.**__* (2019) "Quantitative proteomics of Th-MYCN transgenic mice reveals aurora kinase inhibitor altered metabolic pathways and enhanced ACADM to suppress neuroblastoma progression" //Journal of Proteome Research// (Accepted). | + | - Hsieh, C.-H., Huang, C.-T., Cheng, Y.-S., Hsu, C.-H., Hsu, W.-M., Chung, Y.-H., Liu, Y.-L. Yang, T.-S., Chien, C.-Y., Lee, Y.-S., Huang, H.-C.*, __**Juan, H.-F.**__* (2023) "Homoharringtonine as a PHGDH Inhibitor: unraveling metabolic dependencies and developing a potent therapeutic strategy for high-risk neuroblastoma" //Biomedicine & Pharmacotherapy// 166:115**429**. |
- | - Chang, H.-C., Huang, H.-C., __**Juan, H.-F.**__*, Hsu, C.-L* (2019) "Investigating the role of super-enhancer RNAs underlying embryonic stem cell differentiation" //BMC Genomics// (Accepted). | + | - Kao, Y.-C., Chang, Y.-W., Lai, C. P., Chang, N.-W., Huang, C.-H., Huang, H.-C.*, __**Juan, H.-F.**__* (2023) "Ectopic ATP synthase stimulates the secretion of extracellular vesicles in cancer cells" //Communications Biology// 6:642 |
- | - Wu, P.-Y., Yu, I-S., Lin, Y.-C., Chang, Y.-T., Chen, C.-C., Lin, K.-H., Tseng, T.-H., Kargren, M., Tai, Y.-L., Shen, T.-L., Liu, Y.-L., Wang, B.-J., Chang, C.-H., Chen, W.-M., __**Juan, H.-F.**__, Huang, S.-F., Chan, Y.-Y., Liao, Y.-F., Hsu, W.-M., Lee, H. (2019) "Activation of aryl hydrocarbon receptor by kynurenine impairs progression and metastasis of neuroblastoma" //Cancer Research// (in press). | + | - Chang, Y.-W., Yang, T.-T., Chen, M.-C., Liaw, Y.-G., Yin, C.-F., Huang, T.-Y., Hou, J.-T., Hung, Y.-H., Hsu CL, Huang, H.-C.*, __**Juan, H.-F.**__* (2023) "Spatial and temporal dynamics of ATP synthase from mitochondria toward the cell surface" //Communications Biology// 6:42. |
+ | - __**Juan, H.-F.**__* and Huang, H.-C.* (2023) "Quantitative analysis of high-throughput biological data" //WIREs Computational Molecular Science// ([[https://doi.org/10.1002/wcms.1658]]) | ||
+ | - Tu, Y.-H., __**Juan, H.-F.**__* and Huang, H.-C.* (2023) "Context-dependent gene regulatory network reveals regulation dynamics and cell trajectories using unspliced transcripts" //Briefings in Bioinformatics// 24(2):bbac633. | ||
+ | - Hsieh, C.-Y., Wen, J.-H., Lin, S.-M., Tseng, T.-Y., Huang, J.-H., Huang, H.-C.*, __**Juan, H.-F.**__* (2023) "scDrug: From single-cell RNA-seq to drug response prediction" //Computational and Structural Biotechnology Journal// 2:150-157. | ||
+ | - Chen, K.-P., Hsu, C.-L., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2023) "BIC: a database for the transcriptional landscape of bacteria in cancer" //Nucleic Acids Research// 51(D1):D1205-D1211. | ||
+ | - Hsu, C.-L.<sup>#</sup>, Yin, C.-F.<sup>#</sup>, Chang, Y.-W., Fan, Y.-C., Lin, S.-H., Wu, Y.-C., Huang, H.-C.*, __**Juan, H.-F.**__* (2022) "LncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/2" //Cell Death & Disease// 13:809. | ||
+ | - Wu, S.-Y., Wu, H.-T., Wang, Y.-C., Chang, C.-J., Shan, Y.-S., Wu, S.-R., Chiu, Y.-C., Hsu, C.-L., __**Juan, H.-F.**__, Lan, K.-Y., Chu, C.-W., Lee, Y.-R., Lan, S.-H., Liu, H.-S. (2022) "Secretory autophagy promotes RAB37-mediated insulin secretion under glucose stimulation both in vitro and in vivo" //Autophagy// Sep 15:1-19. doi: 10.1080/15548627.2022.2123098. | ||
+ | - Li, P.-H., Chen, T.-F., Yu, J.-Y., Shih, S.-H., Su, C.-H., Lin, Y.-H., Tsai, H.-K., __**Juan, H.-F.**__, Chen, C.-Y., Huang, J.-H. (2022) "pubmedKB: an interactive web server for exploring biomedical entity relations in the biomedical literature" //Nucleic Acids Research// 50(W1):W616-W622. | ||
+ | - Chang, Y.-W., Wang, C.-C, Yin, C.-F., Wu, C.-H., Huang, H.-C.*, __**Juan, H.-F.**__* (2022) "Quantitative phosphoproteomics reveals ectopic ATP synthase on mesenchymal stem cells to promote tumor progression via ERK/c-Fos pathway activation" //Molecular & Cellular Proteomics// 21(6):100237. | ||
+ | - Li, A., Chen, J.-Y., Hsu, C.-L., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2022) "A single-cell network-based drug repositioning strategy for post-COVID-19 pulmonary fibrosis" //Pharmaceutics// 14:971. | ||
+ | - Lee, R. K.-L., Li, T.-N., Chang, S.-Y., Chao, T.-L., Kuo, C.-H., Pan, M. Y.-C., Chiou, Y.-T., Liao, K.-J., Yang, Y., Wu, Y.-H., Huang, C.-H., __**Juan, H.-F.**__, Hsieh, H.-P., Wang, L. H.-C. (2022) "Identification of entry inhibitors against delta and omicron variants of SARS-CoV-2" //International Journal of Molecular Sciences// 23:4050. | ||
+ | - Yin, C.-F.<sup>#</sup>, Chang, Y.-W.<sup>#</sup>, Huang, H.-C.*, __**Juan, H.-F.**__* (2022) "Targeting protein interaction networks in mitochondria dynamics for cancer therapy" //Drug Discovery Today// 27(4): 1077-1087. | ||
+ | - Ko, K.-Y., Chen, C.-Y., __**Juan, H.-F.**__* and Huang, H.-C.* (2022) "Phylotranscriptomic patterns of network stochasticity and pathway dynamics during embryogenesis" //Bioinformatics// 38(3):763-769. | ||
+ | - Chang, C.-S.<sup>#</sup>, Yu, W.-H.<sup>#</sup>, Ruan, J.-W., Huang, C.-T., Lin, C.-M., Tsai, Y.-T., Lin, I-J., Lai, C.-Y., Chang, C.-W., Chuang, T.-H., Lin, W.-J., Tan, T.-H., Huang, H.-C., __**Juan, H.-F.**__ and Kao, C.-Y.* (2022) "Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice" //iScience// 25(2):103738. | ||
+ | - Yu, P.-C.<sup>#</sup>, Huang, C.-H.<sup>#</sup>, Kuo, C.-J., Liang, P.-H., Wang, L.H.-C., Pan, M. Y.-C., Chang, S.-Y. Chao, T.-L., Ieong, S., Fang, J.-T., Huang, H.-C.*, __**Juan, H.-F.**__* (2022) "Drug repurposing for the identification of compounds with anti-SARS-CoV-2 capability via multiple targets" //Pharmaceutics// 14:176. | ||
+ | - Hsieh, C.-H.<sup>#</sup>, Yeh, H.-N.<sup>#</sup>, Huang, C.-T., Wang, W.-H., Hsu, W.-M., Huang, H.-C.*, __**Juan, H.-F.**__* (2022) "BI-2536 Promotes Neuroblastoma Cell Death via Minichromosome Maintenance Complex Components 2 and 10" //Pharmaceuticals// 15:37. | ||
+ | - Li, A., Yu, W.-H., Hsu, C.-L., Huang, H.-C.*, __**Juan, H.-F.**__* (2021) "Modular signature of long non-coding RNA association networks as a prognostic biomarker in lung cancer" //BMC Medical Genomics// 14:290. | ||
+ | - Chang, C.-S., Liao, Y.-C., Huang, C.-T., Lin, C.-M., Cheung, C. H. Y., Ruan, J.-W., Yu, W.-H., Tsai, Y.-T., Lin, I-J., Huang, C.-H., Liou, J.-S., Chou, Y.-H., Chien, H.-J., Chuang, H.-L., __**Juan, H.-F.**__, Huang, H.-C., Chan, H.-L., Liao, Y.-C., Tang, S.-C., Su, Y.-W., Tan, T.-H., Bäumler, A. J., Kao, C.-Y.* (2021) "Discovery of a novel microbiota member that ameliorates dss-induced colitis in gut barrier enhanced Dusp6-deficient mice" //Cell Reports// 37:110016. | ||
+ | - Tu, Y.-H., __**Juan, H.-F.**__* and Huang, H.-C.* (2021) "Identification of cell states using super-enhancer RNA" //BMC Genomics// 22:787. | ||
+ | - Lee, K.-H., Chang, Y.-C., Chen, T.-F., __**Juan, H.-F.**__, Tsai, H.-K., Chen, C.-Y. (2021) "Connecting MHC-I-binding motifs with HLA alleles via deep learning" //Communications Biology// 4:1194. | ||
+ | - Li, A., Huang, H.-T., Huang, H.-C.*, __**Juan, H.-F.**__* (2021) "LncTx: A network-based method to repurpose drugs acting on the survival-related lncRNAs in lung cancer" //Computational and Structural Biotechnology Journal// 19:3990-4002. | ||
+ | - Lee, T.-T., Chen, P.-L., Su, M. P., Li, J.-C., Chang, Y.-W., Liu, R.-W., __**Juan, H.-F.**__, Yang, J.-M., Chan, S.-P., Tsai, Y.-C., von Stockum, S., Ziviani, E., Kamikouchi, A., Wang, H.-D. , Chen, C.-H. (2021) "Loss of Fis1 impairs proteostasis during skeletal muscle aging in Drosophila" //Aging Cell// 20(6):e13379. | ||
+ | - Wang, W.-H., Chen, S.-K., Huang, H.-C.*, __**Juan, H.-F.**__* (2021) "Proteomic analysis reveals metformin suppresses PSMD2, STIP1 and CAP1 for anti-gastric cancer AGS cell proliferation and migration" //ACS Omega// 6(22):14208-14219. | ||
+ | - Peng, C., Li, Y.-H., Yu, C.-W., Cheng, J.-H., Liu, J.-R., Hsu, J.-L., Hsin, L.-W., Huang, C.-T., __**Juan, H.-F.**__, Chern, J.-W., Cheng, Y.-S. (2021) "Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity" //Bioorganic Chemistry// 110:104813. | ||
+ | - Chen, T.-F., Chang, Y.-C., Hsiao, Y., Lee, K.-H., Hsiao, Y.-C., Lin, Y.-H., Tu, Y.-C. E., Huang, H.-C., Chen, C.-Y.*, __**Juan, H.-F.**__* (2021) "DockCoV2: a drug database against SARS-CoV-2" //Nucleic Acids Research// 49(D1):D1152-D1159. | ||
+ | - Huang, C.-T., Chao, T.-L., Kao, H.-C., Pang, Y.-H., Lee, W.-H., Hsieh, C.-H., Chang, S.-Y.*, Huang, H.-C.*, __**Juan, H.-F.**__* (2020) "Enhancement of the IFN-β-induced host signature informs repurposed drugs for COVID-19" Heliyon 6(12):e05646 (Cell Press). | ||
+ | - Chang, Y.-W., Hsu, C.-L., Tang, C.-W., Chen, X.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2020) "Multiomics reveals ectopic ATP synthase blockade induces cancer cell death via a lncRNA-mediated phospho-signaling network" //Molecular and Cellular Proteomics// 19(11):1805-1825. | ||
+ | - Wu, A. Y.-T., Sun, Y.-C., Chen, Y.-J., Chou, S. T.-Y., Guo, V., Chien, J. C.-Y., Ko, J. J.-S., Yang, A. L., Huang, H.-C., Chuang, J.-C., Wu, S., Ho, M.-R., Ericsson, M., Lin, W.-W., Cheung, C. H. Y., __**Juan, H.-F.**__, Ueda, K., Chen Y., Lai C. P.-K. (2020) "Multi-resolution imaging using bioluminescence resonance energy transfer identifies distinct biodistribution profiles of extracellular vesicles and exomeres with redirected tropism" //Advanced Science// 7: 2001467. | ||
+ | - Cheung, H. Y. C., Hsu, C.-L., Lin, T.-Y., Chen, W.-T., Wang, Y.-C., Huang, H.-C.*, __**Juan, H.-F.**__* (2020) "ZNF322A-mediated protein phosphorylation induces autophagosome formation through modulation of IRS1-AKT glucose uptake and HSP-elicited UPR in lung cancer” //Journal of Biomedical Science// 27(1):75. | ||
+ | - Wang, W.-H., Hsu, C.-L., Huang, H.-C.*, __**Juan, H.-F.**__* (2020) "Quantitative phosphoproteomics reveals cell alignment and mitochondrial length change under cyclic stretching in lung cells" //International Journal of Molecular Sciences// 21(11):E4074. | ||
+ | - Yin, C.-F., Kao, S.-C., Hsu, C.-L., Cheung, C. H.Y., Chang, Y.-W., Huang, H.-C.*, __**Juan, H.-F.**__* (2020) "Phosphoproteome analysis reveals dynamic heat shock protein 27 phosphorylation in tanshinone IIA-induced cell death" //Journal of Proteome Research// 19(4):1620-1634. | ||
+ | - Lee, P.-C. Chen, S.-T., Kuo, T.-C., Lin, T.-C., Lin, M.-C., Huang, J., Hung, J.-S., Hsu, C.-L., __**Juan, H.-F.**__, Lee, P.-H., and Huang, M.-C. (2020) "C1GALT1 is associated with poor survival and promotes soluble Ephrin A1-mediated cell migration through activation of EPHA2 in gastric cancer" //Oncogene// 39(13):2724-2740. | ||
+ | - Lee, W.-H., Chen, K.-P., Wang, K., Huang, H.-C.*, __**Juan, H.-F.**__* (2020) "Characterizing the cancer-associated microbiome with small RNA sequencing data" //Biochemical and Biophysical Research Communications// 522:776-782. | ||
+ | - Chang, H.-C., Huang, H.-C., __**Juan, H.-F.**__*, Hsu, C.-L* (2019) "Investigating the role of super-enhancer RNAs underlying embryonic stem cell differentiation" //BMC Genomics// 20(Suppl 10):896. | ||
+ | - Hsieh, C.-H., Cheung, C. H. Y., Liu, Y.-L., Hou, C.-L., Hsu, C.-L., Huang, C.-T., Yang, T.-S., Chen, S.-F., Chen, C.-N., Hsu, W.-M.*, Huang, H.-C.*, __**Juan, H.-F.**__* (2019) "Quantitative proteomics of Th-MYCN transgenic mice reveals aurora kinase inhibitor altered metabolic pathways and enhanced ACADM to suppress neuroblastoma progression" //Journal of Proteome Research// 18(11):3850-3866. | ||
+ | - Cheung, H. Y. C., Hsu, C.-L., Tsuei, C.-Y., Kuo, T.-T., Huang, C.-T., Hsu, W.-M., Chung, Y.-H., Wu, H.-Y., Hsu, C.-C., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) "Combinatorial targeting of MTHFD2 and PAICS in purine synthesis as a novel therapeutic strategy" //Cell Death & Disease// 10:786. | ||
+ | - Wu, P.-Y., Yu, I-S., Lin, Y.-C., Chang, Y.-T., Chen, C.-C., Lin, K.-H., Tseng, T.-H., Kargren, M., Tai, Y.-L., Shen, T.-L., Liu, Y.-L., Wang, B.-J., Chang, C.-H., Chen, W.-M., __**Juan, H.-F.**__, Huang, S.-F., Chan, Y.-Y., Liao, Y.-F., Hsu, W.-M., Lee, H. (2019) "Activation of aryl hydrocarbon receptor by kynurenine impairs progression and metastasis of neuroblastoma" //Cancer Research// 79(21):5550-5562. | ||
- Huang, C.-T., Hsieh, C.-H., Lee, W.-C., Liu, Y.-L., Yang, T.-S., Hsu, W.-M., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) "Therapeutic targeting of non-oncogene dependencies in high-risk neuroblastoma" //Clinical Cancer Research// 25(13):4063-4078. | - Huang, C.-T., Hsieh, C.-H., Lee, W.-C., Liu, Y.-L., Yang, T.-S., Hsu, W.-M., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) "Therapeutic targeting of non-oncogene dependencies in high-risk neuroblastoma" //Clinical Cancer Research// 25(13):4063-4078. | ||
- Huang, C.-T., Hsieh, C.-H., Chung, Y.-H., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) "Perturbational gene-expression signatures for combinatorial drug discovery" //iScience// 15:291-306 (**Cell Press**). | - Huang, C.-T., Hsieh, C.-H., Chung, Y.-H., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) "Perturbational gene-expression signatures for combinatorial drug discovery" //iScience// 15:291-306 (**Cell Press**). | ||
- Yang, T.-W., Sahu, D., Chang, Y.-W., Hsu, C.-L., Hsieh, C.-H., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) “RNA-binding proteomics reveals MATR3 interacting with lncRNA SNHG1 to enhance neuroblastoma progression” //Journal of Proteome Research// 18: 406–416. | - Yang, T.-W., Sahu, D., Chang, Y.-W., Hsu, C.-L., Hsieh, C.-H., Huang, H.-C.*, __**Juan, H.-F.**__* (2019) “RNA-binding proteomics reveals MATR3 interacting with lncRNA SNHG1 to enhance neuroblastoma progression” //Journal of Proteome Research// 18: 406–416. | ||
- | - Chang, J.-Y., Yu, W.-H., __**Juan, H.-F.**__*, Huang, H.-C.* (2018) "Dynamics of alternative polyadenylation in human preimplantation embryos" //Biochemical and Biophysical Research// Sep 11. pii: S0006-291X(18)31946-6. | + | - Chang, J.-Y., Yu, W.-H., __**Juan, H.-F.**__*, Huang, H.-C.* (2018) "Dynamics of alternative polyadenylation in human preimplantation embryos" //Biochemical and Biophysical Research Communications// 504(4):727-733. |
- Huang, C.-T., Hsieh, C.-H., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2018) "A large-scale gene expression intensity-based similarity metric for drug repositioning" //iScience// 7: 40-52. (Cell Press) | - Huang, C.-T., Hsieh, C.-H., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2018) "A large-scale gene expression intensity-based similarity metric for drug repositioning" //iScience// 7: 40-52. (Cell Press) | ||
- Lin, M.-C., Chien, P.-H., Wu, H.-Y., Chen, S.-T., __**Juan, H.-F.**__, Lou, P.-J.*, Huang, M.-C. (2018) "C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer" //Oncogene// Jun 21. doi: 10.1038/s41388-018-0375-0. | - Lin, M.-C., Chien, P.-H., Wu, H.-Y., Chen, S.-T., __**Juan, H.-F.**__, Lou, P.-J.*, Huang, M.-C. (2018) "C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer" //Oncogene// Jun 21. doi: 10.1038/s41388-018-0375-0. | ||
- Sahu, D., Ho, S.-Y., __**Juan, H.-F.**__*, Huang, H.-C.* (2018) "High-risk, expression-based prognostic long noncoding RNA signature in neuroblastoma" //JNCI Cancer Spectrum// 2(2): pky015. | - Sahu, D., Ho, S.-Y., __**Juan, H.-F.**__*, Huang, H.-C.* (2018) "High-risk, expression-based prognostic long noncoding RNA signature in neuroblastoma" //JNCI Cancer Spectrum// 2(2): pky015. | ||
- | - Cheng, A.-N., Fan, C.-C., Lo, Y.-K., Kuo, C.-L., Wang, H.-C., Lien, I-H., Lin, S.-Y., Chen, C.-H., Jiang, S. S., Chang, I-S., __**Juan, H.-F.**__, Lyu, P.-C., Lee, A Y.-L.* "Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer" //Scientific Reports// 7: 17024. | + | - Cheng, A.-N., Fan, C.-C., Lo, Y.-K., Kuo, C.-L., Wang, H.-C., Lien, I-H., Lin, S.-Y., Chen, C.-H., Jiang, S. S., Chang, I-S., __**Juan, H.-F.**__, Lyu, P.-C., Lee, A Y.-L.* (2017) "Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer" //Scientific Reports// 7: 17024. |
- Cheung, H. Y. C., Hsu, C.-L., Chen, K.-P., Chong, S.-T., Huang, H.-C.*, __**Juan, H.-F.**__* (2017) "MCM2-regulated functional networks in lung cancer by multi-dimensional proteomic approach" //Scientific Reports// 7(1):13302. | - Cheung, H. Y. C., Hsu, C.-L., Chen, K.-P., Chong, S.-T., Huang, H.-C.*, __**Juan, H.-F.**__* (2017) "MCM2-regulated functional networks in lung cancer by multi-dimensional proteomic approach" //Scientific Reports// 7(1):13302. | ||
- Hsu, C.-L., Wang, J.-K., Lu, P.-C., Huang, H.-C.*, and __**Juan, H.-F.**__* (2017) "DynaPho: a web platform for inferring the dynamics of time-series phosphoproteomics" //Bioinformatics// 33(22):3664-3666. | - Hsu, C.-L., Wang, J.-K., Lu, P.-C., Huang, H.-C.*, and __**Juan, H.-F.**__* (2017) "DynaPho: a web platform for inferring the dynamics of time-series phosphoproteomics" //Bioinformatics// 33(22):3664-3666. | ||
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- __**Juan, H.-F.**__, Hung, C.-C., Wang, K.-T., Chiou, S.-H.* (1999) “Comparison of three classes of snake neurotoxins by homology modeling and computer simulation graphics.” Biochem Biophys Res Commun. 257: 500-510. | - __**Juan, H.-F.**__, Hung, C.-C., Wang, K.-T., Chiou, S.-H.* (1999) “Comparison of three classes of snake neurotoxins by homology modeling and computer simulation graphics.” Biochem Biophys Res Commun. 257: 500-510. | ||
===== Conference Proceedings / 研討會論文 ===== | ===== Conference Proceedings / 研討會論文 ===== | ||
+ | - Kuo, C.-H., Chang, Y.-W., Huang, H.-C.*, __**Juan, H.-F.**__* "Drug repositioning for neuroblastoma therapy via targeting dihydroorotate dehydrogenase in mitochondrial dynamics " //37th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 18-19, 2023. (**Best Poster Award**) | ||
+ | - Chen, Y.-X., Li, A., Hsieh, C.-H., Chang, Y.-W., Huang, H.-C.*, __**Juan, H.-F.**__* "Drug discovery for high-risk neuroblastoma via targeting tumor heterogeneity at single-cell level" //37th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 18-19, 2023. | ||
+ | - Wen, J.-H., Hsieh, C.-Y., Huang, J.-H.*, __**Juan, H.-F.**__*, Huang, H.-C.* "Gene expression dispersion reflects the disease state from single-cell transcriptomic data" //Multiomics and Precision Medicine Joint Conference//, Taipei, Taiwan, Nov. 19-20, 2022. (**Best Poster Award**) | ||
+ | - Sun, Y.-Y., Wang, X.-C., Chang, Y.-W., Hsu, C.-L., Huang, H.-C.* and __**Juan, H.-F.**__* "single-cell RNA-seq analysis reveals the effect of tunneling nanotubes (TNTs)-mediated transfer under hypoxic stress in neuroblastoma" //Multiomics and Precision Medicine Joint Conference//, Taipei, Taiwan, Nov. 19-20, 2022. (**Best Poster Award**) | ||
+ | - Chang, Y.-W., Wang, X.-C., Sun, Y.-Y., Chang, T.-Y., Huang, H.-C.* and __**Juan, H.-F.**__* "Tunneling nanotube-mediated intercellular transfer rescues neuroblastoma cells from hypoxic stress" //Multiomics and Precision Medicine Joint Conference//, Taipei, Taiwan, Nov. 19-20, 2022. (**1st Prize**) | ||
+ | - Tseng, T.-Y., Hsu, C.-L., Ou, D.-L., Hsu, C., Huang, C.-T., Huang, H.-C.* and __**Juan, H.-F.**__* "Single-cell multi-omics analysis reveals transcriptional regulatory network of CD8+ T cell exhaustion under anti-PD-1 resistance in hepatocellular carcinoma and predicts potential small molecular drug to avoid T cell dysfunction" //Multiomics and Precision Medicine Joint Conference//, Taipei, Taiwan, Nov. 19-20, 2022. (**Best Poster Award**) | ||
+ | - Chen, K.-P., Hsu, C.-L., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* "BIC: a database for the transcriptional landscape of bacteria in cancer" //Multiomics and Precision Medicine Joint Conference//, Taipei, Taiwan, Nov. 19-20, 2022. (**Best Poster Award**) | ||
+ | - Yu, P.-C., Kao, Y.-C., Huang, C.-T., Chang, H.-Y., Huang, C.-H., Huang H.-C.*, __**Juan, H.-F.**__* ” Combination therapy of targeting mTOR signaling pathway and mitochondria respiration for high-risk neuroblastoma” //Multiomics and Precision Medicine Joint Conference//, Taipei, Taiwan, Nov. 19-20, 2022. | ||
+ | - Hsieh, C.-H., Huang, C.-T., Chang, K.-J., Liu, J.-U., Huang, H.-C.* and __**Juan, H.-F.**__* "Targeting drug-induced transcriptional mechanisms to guide effective cancer therapy" //Multiomics and Precision Medicine Joint Conference//, Taipei, Taiwan, Nov. 19-20, 2022. (**Honorable Award**) | ||
+ | - Lin-Yan, X.-Q., Chang, Y.-W., Huang, H.-C.* and __**Juan, H.-F.**__* "A mitochondria-plasma membrane fusion machinery regulates mitochondrial ATP synthase translocation to the cell surface" //36th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 26-27, 2022. (**Best Poster Award**) | ||
+ | - Wang, X.-C., Chang, Y.-W., Chang T.-Y., Sun Y.-Y., Huang, H.-C.* and __**Juan, H.-F.**__* "Tunneling nanotube-mediated intercellular transfer rescues neuroblastoma cells from hypoxic stress" //36th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 26-27, 2022. | ||
+ | - Chang, K.-J., Huang, C.-T., Hsieh, C.-H., Huang, H.-C.,* and __**Juan, H.-F.**__* "Targeting afatinib-induced transcriptional responses to inform combination therapy for lung cancer" //36th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 25-27, 2022. | ||
+ | - Liu, J.-Y., Huang, C.-T., Hsieh, C.-H., Huang, H.-C.*, and __**Juan, H.-F.**__* "Investigating neratinib-induced cholesterol biosynthesis as a resistance pathway for combinatorial therapy in breast cancer" //36th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 25-27, 2022. | ||
+ | - Tu, Y.-H., __**Juan, H.-F.**__*, Huang, H.-C.* "Context-dependent gene regulatory network explains regulation dynamics and cell trajectories using unspliced transcripts" //International Symposium on Evolutionary Genomics and Bioinformatics 2022 (ISEGB2022)//, March 12-13, 2022. (**Selected oral Presentation**) | ||
+ | - Tseng, T.-Y., Yu, W.-H., Huang, C.-T., Huang, H.-C.*, __**Juan, H.-F.**__* (2022) "Drug Discovery for Triple-negative Breast Cancer by Integrative Single-cell RNA Sequencing and Perturbational Gene-expression Data" //International Symposium on Evolutionary Genomics and Bioinformatics 2022 (ISEGB2022)//, March 12-13, 2022. (**Selected oral Presentation**) | ||
+ | - Ou, P.-Y., __**Juan, H.-F.**__, Huang, H.-C., Hsu, C.-L.* "To investigate the heterogeneity of exhausted T cells across tumor types by integrating single-cell RNA-seq data" //International Symposium on Evolutionary Genomics and Bioinformatics 2022 (ISEGB2022)//, March 12-13, 2022. (**Best Poster Award**) | ||
+ | - Li, A., Chen, J.-Y., Hsu, C.-L., Oyang, Y.-J., Huang, H.-C.*, __**Juan, H.-F.**__* (2022) "Single-cell transcriptome reveals a theragnostic signature for post-COVID-19 pulmonary fibrosis" //International Symposium on Evolutionary Genomics and Bioinformatics 2022 (ISEGB2022)//, March 12-13, 2022. (**Best Poster Award**) | ||
+ | - Wen, J.-H., Hsieh, C.-Y., Huang, J.-H., __**Juan, H.-F.**__*, Huang, H.-C.* "Gene expression dispersion infers COVID-19 severity from single-cell transcriptomic data" //International Symposium on Evolutionary Genomics and Bioinformatics 2022 (ISEGB2022)//, March 12-13, 2022. (**Best Poster Award**) | ||
+ | - Chen, K.-P., Hsu, C.-L., Huang, H.-C.*, __**Juan, H.-F.**__* (2022) "The transcriptional landscape of bacteria in cancers" //International Symposium on Evolutionary Genomics and Bioinformatics 2022 (ISEGB2022)//, March 12-13, 2022. (**Best Poster Award**) | ||
+ | - Yu, W.-H., Oyang, Y.-J., __**Juan, H.-F.**__* Huang, H.-C.* (2022) "Decoding gene co-expression networks of individual cells from single-cell transcriptome" //International Symposium on Evolutionary Genomics and Bioinformatics 2022 (ISEGB2022)//, March 12-13, 2022. | ||
+ | - Lin, C.-Y., __**Juan, H.-F.**__*, Huang, H.-C.* (2022) "Characterization of tumor-associated microbial and transcriptomic signatures in lung adenocarcinoma" //International Symposium on Evolutionary Genomics and Bioinformatics 2022 (ISEGB2022)//, March 12-13, 2022. | ||
+ | - Chen, K.-Y., Chen K.-P., Huang, H.-C.*, __**Juan, H.-F.**__* (2022) "Characterization of the microbiome in the lower respiratory tract of critically ill COVID-19 patients with metatranscriptomic and human transcriptomic data” //International Symposium on Evolutionary Genomics and Bioinformatics 2022 (ISEGB2022)//, March 12-13, 2022. (**Best Poster Award**) | ||
+ | - Chen, J.-Y., Huang, C.-H., Huang, H.-C.*, __**Juan, H.-F.**__* (2022) "Exploring therapy for COVID-19-related heart complications by integrating network-based drug repurposing and single nucleus RNA sequencing" //International Symposium on Evolutionary Genomics and Bioinformatics 2022 (ISEGB2022)//, March 12-13, 2022. | ||
+ | - Huang, C.-H.#, Yu, P.-C.#, Kuo, C.-J., Liang, P.-H., Wang, L.H.-C., Pan, M. Y.-C., Chang, S.-Y. Chao, T.-L., Ieong, S., Fang, J.-T., Huang, H.-C.*, __**Juan, H.-F.**__* (2022) "Drug repurposing for the identification of compounds with anti-SARS-CoV-2 capability via multiple targets" //International Symposium on Evolutionary Genomics and Bioinformatics 2022 (ISEGB2022)//, March 12-13, 2022. | ||
+ | - Chang, Y.-W., Wang, C.-C., Yin, C.-F., Wu, C.-H., Huang, H.-C.*, __**Juan, H.-F.**__* (2021) "Quantitative phosphoproteomics reveals ectopic ATP synthase on mesenchymal stem cells to promote tumor progression via ERK/c-Fos pathway activation" //HUPO ReCONNECT 2021//, online, Nov. 15-19, 2021. | ||
+ | - Hsu, C.-L., Yin, C.-F., Chang, Y.-W., Fan, Y.-C., Lin, S.-H., Wu, Y.-C., Huang, H.-C.*, __**Juan, H.-F.**__* (2021) "LncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/2" //The Taiwan Society for Biochemistry and Molecular Biology Autumn Camp//, online, Oct. 16-17, 2021. | ||
+ | - Chang, Y.-W., Wang, C.-C, Yin, C.-F., Wu, C.-H., Huang, H.-C.*, __**Juan, H.-F.**__* (2021) "Quantitative phosphoproteomics reveals ectopic ATP synthase on mesenchymal stem cells to promote tumor progression via ERK/c-Fos pathway activation" //The Taiwan Society for Biochemistry and Molecular Biology Autumn Camp//, online, Oct. 16-17, 2021. | ||
+ | - Wang, W.-H., Tsai, S.-Y., Hsieh, C.-H., Cheung, C. H. Y., Huang, H.-C.*, __**Juan, H.-F.**__* (2021) "Integrative proteomics and phosphoproteomics reveal that mitochondrial division inhibitor 1 enhances serine synthesis and dephosphorylates PSMA3-S250 in neuroblastoma" //10th Asia-Oceania Human Proteome Organization (AOHUPO) Congress//, Busan, Korea, June 30 - July 2, 2021. | ||
+ | - Chen, K.-P., Hsu, C.-L., Huang, H.-C.*, __**Juan, H.-F.**__* (2021) "Identification of the cancers-associated microbiome with microRNA-seq" //2021 Annual Conference of Taiwan Microbiota Consortium (2021 ACTMC)//, Taipei, Taiwan, April 24, 2021. | ||
+ | - Chang, Y.-W., Yang, T. T., Chen, M.-C., Liaw, Y-g., Yin, C.-F., Huang, T.-Y., Hou, J.-T., Hung, Y.-H., Hsu, C.-L., Huang, H.-C. *, __**Juan, H.-F.**__* "Mitochondrial ATP Synthase Trafficking along Microtubules to the Cell Surface Depends on KIF5B and DRP1" 2020 Annual Meeting of Taiwan Society for Mitochondrial Research and Medicine, Hualien, Taiwan, Nov. 14-15, 2020. (**Honorable Award**) | ||
+ | - Hsieh, C.-H., Huang, C.-T., Cheng, Y.-S., Chung, Y.-H., Liu, Y.-L., Hsu, C.-H., Hsu, W.-M., Huang, H.-C.*, __**Juan, H.-F.**__* "Identification of a new phosphoglycerate dehydrogenase inhibitor to reprogram serine/glycine metabolism for neuroblastoma therapy" 2020 The Taiwan Society for Biochemistry and Molecular Autumn Camp, Taina, Taiwan, Oct. 30- Nov. 1, 2020. (**Excellent Poster Award**) | ||
+ | - Wang, W.-H., Tsai, H.-H., Hsieh, C.-H., Huang, C.-T., Cheung, C. H. Y., Huang, H.-C., __**Juan, H.-F.**__* "Mitochondrial Division Inhibitor 1 induced serine biosynthesis via regulation of PSMA3-S250 in neuroblastoma" 2020 The Taiwan Society for Biochemistry and Molecular Autumn Camp, Taina, Taiwan, Oct. 30- Nov. 1, 2020. | ||
+ | - Chang, H.-C., Huang, H.-C., __**Juan, H.-F.**__*, Hsu, C.-L* (2019) "Investigating the role of super-enhancer RNAs underlying embryonic stem cell differentiation" //Joint 30th International Conference on Genome Informatics& Australasian Bioinformatics and Computational Biology Society (GIW/ABACBS 2019)//, Sydney, Australia, Dec. 9-11, 2019. (**Oral Presentation**) | ||
+ | - Cheung, C.H.Y., Hsu, C.-L., Lin, T.-Y., Chen, W.-T., Wang, Y.-C., Huang, H.-C.*, and __**Juan, H.-F.**__* "Quantitative Proteomics and Phosphoproteomics Analyses Reveal the Regulatory Roles of ZNF322A in lung cancer" //2019 Multiomics and precision medicine joint conference//, Tainan, Taiwan, Dec. 07-08, 2019. (**Young scientist oral presentation competition - 2nd place**) | ||
+ | - Lee, W.-H., Chen, K.-P., Wang, K., Huang, H.-C.*, and __**Juan, H.-F.**__* "Characterizing the cancer-associated microbiome with small RNA sequencing data" //2019 Multiomics and precision medicine joint conference//, Tainan, Taiwan, Dec. 07-08, 2019. (**Poster Award**) | ||
+ | - Hsieh, C.-H., Cheung, C.H.-Y., Liu, Y.-L., Hou, C.-L., Hsu, C.-L., Huang, C.-T., Yang, T.-S., Chen, S.-F., Chen, C.-N., Hsu, W.-M.*, Huang, H.-C*. and __**Juan, H.-F.**__* "Quantitative Proteomics of Th-MYCN Transgenic Mice Reveals Aurora Kinase Inhibitor Altered Metabolic Pathways and Enhanced ACADM To Suppress Neuroblastoma Progression" //2019 Multiomics and precision medicine joint conference//, Tainan, Taiwan, Dec. 07-08, 2019. (**Poster Award**) | ||
+ | - Kao, Y.-C., Chang, N.-W., Lai, C.P., Huang, H.-C.*, and __**Juan, H.-F.**__* " The role of ectopic ATP synthase in cell-to-cell communication by extracellular vesicles" //2019 The Taiwan Society for Biochemistry and Molecular Autumn Camp//, New Taipei City, Taiwan, Nov. 15-17, 2019. | ||
+ | - Chang, Y.-W., Hou, J.-T., Liaw, Y-g., Huang, T.-Y., Chen, M.-C., Yin, C.-F., Hung, Y.-H., Hsu, C.-L., Huang, H.-C.*, and __**Juan, H.-F.**__* "Mitochondrial ATP synthase trafficking toward the cell surface depending on KIF5B and Drp1 to serve as a new target for overcoming chemoresistance" //2019 Annual Meeting of Taiwan Society for Mitochondrial Research and Medicine//, Taipei, Taiwan, Nov. 09, 2019. (**Honorable Award**) | ||
+ | - Wang, W. H., Hsu, C. L., Huang, H.-C.*, and __**Juan, H.-F.**__* "Cyclic stretch-induced biological functions by phosphoproteomics profiling" //2019 Annual Meeting of Taiwan Society for Mitochondrial Research and Medicine//, Taipei, Taiwan, Nov. 09, 2019. (**Honorable Award**) | ||
+ | - __**Juan, H.-F.**__* and Huang, H.-C.* "Targeting Trafficking of Mitochondrial Key Energy Protein for Cancer Therapy" //16th conference of The Asian Society for Mitochondrial Research and Medicine (ASMRM2019)//, Fukuoka city, Japan, Oct. 3-5, 2019 (**E-poster**) | ||
+ | - Huang, C.-T., Hsieh, C.-H., Lee, W.-C., Liu, Y.-L., Yang, T.-S., Hsu, W.-M., Oyang, Y.-J., Huang, H.-C.* and __**Juan, H.-F.**__* "Therapeutic targeting of non-oncogene dependencies in high-risk neuroblastoma " //The 78th Annual Meeting of the Japanese Cancer Association//, Kyoto, Japan, Sep. 26-28, 2019. (**Travel Grant Award**) | ||
+ | - Hsieh, C.-H., Cheung, C. H. Y., Liu, Y.-L., Hou, C.-L., Hsu, C.-L., Huang, C.-T., Yang, T.-S., Chen, S.-F., Chen, C.-N., Hsu, W.-M.*, Huang, H.-C.* and __**Juan, H.-F.**__* "Targeting aurora kinases reduces neuroblastoma progression by altering the metabolic pathways via enhancing ACADM" //The 78th Annual Meeting of the Japanese Cancer Association//, Kyoto, Japan, Sep. 26-28, 2019. (**Travel Grant Award**) | ||
- Kao, Y.-C., Chang, N.-W., Chang, Y.-W., Lai, C. P., Huang, H.-C. and __**Juan, H.-F.**__* "Ectopic ATP synthase induces extracellular vesicle release for cell-to-cell communications" The 8th Congress of the International Society for Extracellular Vesicles (ISEV2019), Kyoto, Japan, April 24-28, 2019. | - Kao, Y.-C., Chang, N.-W., Chang, Y.-W., Lai, C. P., Huang, H.-C. and __**Juan, H.-F.**__* "Ectopic ATP synthase induces extracellular vesicle release for cell-to-cell communications" The 8th Congress of the International Society for Extracellular Vesicles (ISEV2019), Kyoto, Japan, April 24-28, 2019. | ||
- Wang, C.-C., Chang, Y.-W., Wu, C.-H., Cheung, C. H. Y., Lee, J.-L., Huang, H.-C.* and __**Juan, H.-F.**__* "Mesenchymal stem cells-derived microenvironment promote lung cancer cell progression via c-Fos S374 phosphorylation in MAPK signaling pathway" //34th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 23-24, 2019. (**Best Poster Award**) | - Wang, C.-C., Chang, Y.-W., Wu, C.-H., Cheung, C. H. Y., Lee, J.-L., Huang, H.-C.* and __**Juan, H.-F.**__* "Mesenchymal stem cells-derived microenvironment promote lung cancer cell progression via c-Fos S374 phosphorylation in MAPK signaling pathway" //34th Joint Annual Conference of Biomedical Sciences//, Taipei, Taiwan, March 23-24, 2019. (**Best Poster Award**) |